The following figure presents blood smear of a woman with a history of pancytopenia and splenomegaly for the last six months. Approximately 35% of her lymphocytes were granular and expressed CD16 and CD56 but were negative for CD3.
1. These lymphocytes represent:
A. Natural killer (NK) cells
B. Cytotoxic T cells
C. Helper T cells
D. Prolymphocytes
2. DND molecular studies may show:
A. Rearranged TCR genes
B. Rearranged Ig genes
C. BCL-2 rearrangement
D. None of the above
ANSWER
