Neuropathology Fellowships

A two-year ACGME-accredited fellowship is available for M.D./D.O. candidates with previous completion of two years of anatomic pathology training, or primary board certification in another specialty (e.g. Neurology, Neurosurgery, other).  Dr. Harry Vinters directs a neuropathology training program designed to provide an in-depth, meaningful, broadly based and rewarding creative and learning experience in neuropathology leading to American Board of Pathology certification in AP/NP, or 'special competence' certification in NP.  The program is closely linked to the two main academic spheres at UCLA CHS, that served by Autopsy, Surgical (Anatomic) and Experimental Pathology, and that served by the Clinical Neurosciences of Neurology, Neurosurgery and Neuroradiology.  Trainees also have the option of attending neuropathology conferences or doing brief rotations at two other teaching institutions---West L.A. VA Medical Center (Neuropathologist Dr. Uwamie Tomiyasu) and Cedars-Sinai Medical Center (Dr. William H. Yong) with unique strengths and interests.  UCLA-CHS Neuropathology also provides diagnostic support for the Kaiser Health Care system in Southern California, generating a large number of unique consultative cases. 

  Close interaction with clinicians (including trainees) in the Neurosciences is a key component of fellowship training--Neuropathology provides or contributes to numerous teaching confer-ences for clinical colleagues.  Likewise, close interactions with basic neuroscientists with myriad interests are facilitated by the close physical proximity of basic neuroscience research to the Section of Neuropathology, and numerous collaborations between individual neuropathologists and basic neuroscience researchers at UCLA-CHS.  Considerable experience is also available in the area of pediatric neuropathology, with significant pediatric and perinatal autopsy material.  UCLA is also a major international center for pediatric epilepsy surgery (a procedure pioneered at this Center) thus considerable experience is acquired in the work-up and study of malformative, neoplastic and inflammatory disorders that are accessioned as surgical specimens.  Trainees are also involved with the diagnostic work-up of a large number  of nerve and muscle biopsy specimens (including muscle enzyme histochemistry, membrane immunocytochemistry, nerve fiber morphometry, analysis of osmicated teased fiber preparations and electron microscopy, as indicated by case material).  Research opportunities are abundant in both translational and basic research (see specific faculty interests below).  

 

REPRESENTATIVE FACULTY PUBLICATIONS: 

JL Twiss, DS Smith, B Chang et al.  Translational control of ribosomal protein L4 mRNA is required for rapid neurite regeneration.  Neurobiology of Disease 2000; 7:416-428. 

JL Twiss, HG Wada, KS Fok, et al.  Duration and magnitute of nerve growth factor signaling depend on the ratio of p75(LNTR) to TrkA.  J Neuroscience Research 1998;  51:442-453. 

PS Mischel, SG Smith, ER Vining, et al.  The extracellular domain of p75(NTR) is necesary to inhibit neurotrophin-3 signaling through TrkA.  J Biological Chemistry 2001;  276:11294-11301. 

MG Catania, PS Mischel, HV Vinters.  Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B.  J Neuropathol Experimental Neurol 2001;  60:711-723. 

HV Vinters, WG Ellis, C Zarow, BW Zaias, WJ Jagust, WJ Mack, HC Chui.  Neuropathologic substrates of ischemic vascular dementia.  J Neuropathol Experimental Neurol 2000;  59:931-945.

 

| Neuropathology | GI/Liver | Transfusion Medicine | Hematopathology |
| Cytopathology | Clinical Microbiology | Surgical Path/Olive View |