Graduate Student Publications

ILENE AUERBACH
Class of 2000
Laboratory of Dr. Harry Vinters

  1. Auerbach ID, Vinters HV
    Effects of anoxia and hypoxia on amyloid precursor protein processing in cerebral microvascular smooth muscle cells.
    J Neuropathol Exp Neurol. 2006 Jun;65(6):610-20.
    PMID: 16783171

  2. Auerbach ID, Sung SH, Wang Z, Vinters HV.
    Smooth muscle cells and the pathogenesis of cerebral microvascular disease ("angiomyopathies").
    Exp Mol Pathol. 2003 Apr;74(2):148-59.
    PMID: 12710946

CYNTHIA BALATONI - (Profile)
Class of 2004
Laboratory of Dr. Mike Teitell

  1. Chen HW, Rainey RN, Balatoni CE, Dawson DW, Troke JJ, Wasiak S, Hong J, McBride H, Koehler CM, Teitell MA, French SW.
    Mammalian PNPase is an Intermembrane Space Ribonuclease That Maintains Mitochondrial Homeostasis.
    Mol Cell Biol. 2006 Sep 11; [Epub ahead of print]
    PMID: 16966381

  2. French SW, Dawson DW, Chen HW, Rainey RN, Sievers SA, Balatoni CE, Wong L, Troke JJ, Nguyen MT, Koehler CM, Teitell MA.
    The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity.
    Cancer Lett. 2007 Apr 18;248(2):198-210. Epub 2006 Aug 28.
    PMID: 16934922 [PubMed - indexed for MEDLINE]

SIMON BEAVEN - (Profile)
Class of 2005
Laboratory of Dr. Peter Tontonoz

  1. Chen M, Bradley MN, Beaven SW, Tontonoz P.
    Phosphorylation of the liver X receptors.
    FEBS Lett. 2006 Sep 4;580(20):4835-41. Epub 2006 Aug 4.
    PMID: 16904112 [PubMed - in process]

  2. Beaven SW, Tontonoz P.
    Related Articles, Links
    Nuclear receptors in lipid metabolism: targeting the heart of dyslipidemia.
    Annu Rev Med. 2006;57:313-29. Review.
    PMID: 16409152

SARAH BECKER-CATANIA
Class of 1994
Laboratory of Dr. Richard Gatti

  1. Sun X, Becker-Catania SG, Chun HH, Hwang MJ, Huo Y, Wang Z, Mitui M, Sanal O, Chessa L, Crandall B, Gatti RA.
    Early diagnosis of ataxia-telangiectasia using radiosensitivity testing.
    J Pediatr. 2002 Jun;140(6):724-31.

  2. Chun HH, Castellvi-Bel S, Wang Z, Nagourney RA, Plaeger S, Becker-Catania SG, Naeim F, Sparkes RS, Gatti RA.
    TCL-1, MTCP-1 and TML-1 gene expression profile in non-leukemic clonal proliferations associated with ataxia-telangiectasia.
    Int J Cancer. 2002 Feb 20;97(6):726-31.

  3. Becker-Catania SG, Chen G, Hwang MJ, Wang Z, Sun X, Sanal O, Bernatowska-Matuszkiewicz E, Chessa L, Lee EY, Gatti RA.
    Ataxia-telangiectasia: phenotype/genotype studies of ATM protein expression, mutations, and radiosensitivity.
    Mol Genet Metab. 2000 Jun;70(2):122-33.

  4. Teraoka SN, Telatar M, Becker-Catania S, Liang T, Onengut S, Tolun A, Chessa L, Sanal O, Bernatowska E, Gatti RA, Concannon P.
    Splicing defects in the ataxia-telangiectasia gene, ATM: underlying mutations and consequences.
    Am J Hum Genet. 1999 Jun;64(6):1617-31.

  5. Park SH, Becker-Catania S, Gatti RA, Crandall BF, Emelin JK, Vinters HV.
    Congenital olivopontocerebellar atrophy: report of two siblings with paleo- and neocerebellar atrophy.
    Acta Neuropathol (Berl). 1998 Oct;96(4):315-21.

MICHAEL CATANIA
Class of 1994
Laboratory of Dr. Harry Vinters

  1. Catania MG, Mischel PS, Vinters HV.
    Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B.
    J Neuropathol Exp Neurol. 2001 Jul;60(7):711-23.

  2. Catania MG, Johnson MW, Liau LM, Kremen TJ, deVellis JS, Vinters HV.
    Hamartin expression and interaction with tuberin in tumor cell lines and primary cultures.
    J Neurosci Res. 2001 Feb 1;63(3):276-83.

JAY H. CHANG
Class of 1998
Laboratory of Dr. Jeffrey Twiss

  1. Willis D, Li KW, Zheng JQ, Chang JH, Smit A, Kelly T, Merianda TT, Sylvester J, van Minnen J, Twiss JL.
    Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons.
    J Neurosci. 2005 Jan 26;25(4):778-91.
    PMID: 15673657 [PubMed - indexed for MEDLINE]

  2. Espineda CE, Chang JH, Twiss J, Rajasekaran SA, Rajasekaran AK. Related Articles, Links
    Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma.
    Mol Biol Cell. 2004 Mar;15(3):1364-73. Epub 2003 Dec 29.
    PMID: 14699059 [PubMed - indexed for MEDLINE]

  3. Chang JH, Mellon E, Schanen NC, Twiss JL.
    Persistent TrkA activity is necessary to maintain transcription in neuronally differentiated PC12 cells.
    J Biol Chem. 2003 Oct 31;278(44):42877-85. Epub 2003 Aug 8.
    PMID: 12909622 [PubMed - indexed for MEDLINE]

HSIAO-WEN CHEN - (Profile)
Class of 2003
Laboratory of Dr. Mike Teitell

  1. Chen, H.-W., Rainey, R.N., Balatoni, C.E., Dawson, D.W., Troke, J.J., Wasiak, S., Hong, J., McBride, H., Koehler, C.M., Teitell, M.A., and French, S.W.
    Mammalian PNPase is an Intermembrane Space Ribonuclease that Maintains Mitochondrial Homeostasis.

    In press, Molecular and Cellular Biology, 2006.
  2. Rainey, R.N., Glavin, J.D., Chen, H.-W., French, S.W., Teitell, M.A., and Koehler, C.M.
    A new function in translocation for the mitochondrial i-AAA protease Yme1: Import of PNPase into the intermembrane space.

  3. French, S.W., Dawson, D.W., Chen, H.-W., Rainey, R.N., Sievers, S.A., Balatoni, C.E., Wong, L., Troke, J.J., Nyugen, M.T.N., Koehler, C.M., and Teitell, M.A.
    The TCL1 Oncoprotein Binds the RNase PH Domains of the PNPase Exoribonuclease Without Affecting its RNA Degrading Activity.
    Cancer Lett. 2007 Apr 18;248(2):198-210. Epub 2006 Aug 28.
    PMID: 16934922 [PubMed - indexed for MEDLINE]

JASON CHRISTIANSEN
Class of 1998
Laboratory of Dr. AK Rajasekaran

  1. Christiansen JJ, Weimbs T, Bander N, Rajasekaran AK.
    Differing effects of microtubule depolymerizing and stabilizing chemotherapeutic agents on t-SNARE-mediated apical targeting of prostate-specific membrane antigen.
    Mol Cancer Ther. 2006 Oct;5(10):2468-73. PMID: 17041090 [PubMed - in process]

  2. Christiansen JJ, Rajasekaran AK.
    Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis.
    Cancer Res. 2006 Sep 1;66(17):8319-26.
    PMID: 16951136

  3. Anilkumar G, Barwe SP, Christiansen JJ, Rajasekaran SA, Kohn DB, Rajasekaran AK. Related Articles, Links
    Association of prostate-specific membrane antigen with caveolin-1 and its caveolae-dependent internalization in microvascular endothelial cells: implications for targeting to tumor vasculature.
    Microvasc Res. 2006 Jul-Sep;72(1-2):54-61. Epub 2006 May 19.
    PMID: 16713605

  4. Christiansen JJ, Rajasekaran SA, Inge L, Cheng L, Anilkumar G, Bander NH, Rajasekaran AK.
    N-glycosylation and microtubule integrity are involved in apical targeting of prostate-specific membrane antigen: implications for immunotherapy.
    Mol Cancer Ther. 2005 May;4(5):704-14.
    PMID: 15897234 [PubMed - indexed for MEDLINE]

  5. Rajasekaran AK, Anilkumar G, Christiansen JJ.
    Is prostate-specific membrane antigen a multifunctional protein?
    Am J Physiol Cell Physiol. 2005 May;288(5):C975-81. Review.
    PMID: 15840561

  6. Christiansen JJ, Rajasekaran SA, Moy P, Butch A, Goodglick L, Gu Z, Reiter RE, Bander NH, Rajasekaran AK. Polarity of prostate specific membrane antigen, prostate stem cell antigen, and prostate specific antigen in prostate tissue and in a cultured epithelial cell line.
    Prostate. 2003 Apr 1;55(1):9-19.
    PMID: 12640656

HELEN H. CHUN
Class of 1995
Laboratory of Dr. Richard Gatti

  1. Butch AW, Chun HH, Nahas SA, Gatti RA.
    Immunoassay to measure ataxia-telangiectasia mutated protein in cellular lysates.
    Clin Chem. 2004 Dec;50(12):2302-8. Epub 2004 Oct 14.

  2. Chun HH, Cary RB, Lansigan F, Whitelegge J, Rawlings DJ, Gatti RA. 
    ATM protein purified from vaccinia virus expression system: DNA binding requirements for kinase activation.
    Biochem Biophys Res Commun. 2004 Sep 10;322(1):74-81.

  3. Chun HH, Sun X, Nahas SA, Teraoka S, Lai CH, Concannon P, Gatti RA. 
    Improved diagnostic testing for ataxia-telangiectasia by immunoblotting of nuclear lysates for ATM protein expression.
    Mol Genet Metab. 2003 Dec;80(4):437-43.

  4. Sun X, Becker-Catania SG, Chun HH, Hwang MJ, Huo Y, Wang Z, Mitui M, Sanal O, Chessa L, Crandall B, Gatti RA. 
    Early diagnosis of ataxia-telangiectasia using radiosensitivity testing.
    J Pediatr. 2002 Jun;140(6):724-31.

  5. Chun HH, Castellvi-Bel S, Wang Z, Nagourney RA, Plaeger S, Becker-Catania SG, Naeim F, Sparkes RS, Gatti RA. 
    TCL-1, MTCP-1 and TML-1 gene expression profile in non-leukemic clonal proliferations associated with ataxia-telangiectasia.
    Int J Cancer. 2002 Feb 20;97(6):726-31.

OFFER COHAVY
Class of 1995
Laboratory of Dr. Jonathan Braun

  1. Kassan H, Cohavy O, Rosenbaum JT, Braun J, Gordon LK.
    Uveitis seroreactivity to candidate pANCA antigens: mycobacterial HupB and histone H1(69-171).
    Ocul Immunol Inflamm. 2005 Apr-Jun;13(2-3):191-8.

  2. Landers CJ, Cohavy O, Misra R, Yang H, Lin YC, Braun J, Targan SR. 
    Selected loss of tolerance evidenced by Crohn's disease-associated immune responses to auto- and microbial antigens.
    Gastroenterology. 2002 Sep;123(3):689-99.

  3. Cohavy O, Harth G, Horwitz M, Landers C, Sutton C, Targan SR, Braun J.
    Identification of a novel mycobacterial histone H1 homologue (HupB) as an antigenic target of pANCA monoclonal antibody and serum IgA from patients with Crohn’s disease.
    999. Infect. Immun. 67:6510-7

  4. Cohavy O, Bruckner D, Eggena ME, Targan SR, Gordon LK, Braun J.
    Colonic Bacteria Express an Ulcerative Colitis pANCA-Related Protein Epitope
    2000. Infect Immun. 68:1542-8.

  5. Landers CJ, Cohavy O, Misra R, Yang H, Lin YC, Braun J, Targan SR.
     Selected loss of tolerance by Crohn's disease-associated immune responses to auto- and microbial antigens.
    2002. Gastroenterology 123:689-699.

MIRABELLE DAGARAG
Class of 1996
Laboratory of Dr. Rita Effros

  1. Effros RB, Dagarag M, Spaulding C, Man J. 
    The role of CD8+ T-cell replicative senescence in human aging.
    Immunol Rev. 2005 Jun;205:147-57. Review.

  2. Yang OO, Lin H, Dagarag M, Ng HL, Effros RB, Uittenbogaart CH.  
    Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes.
    Virology. 2005 Feb 5;332(1):16-9.

  3. Dagarag M, Evazyan T, Rao N, Effros RB. 
    Genetic manipulation of telomerase in HIV-specific CD8+ T cells: enhanced antiviral functions accompany the increased proliferative potential and telomere length stabilization.
    J Immunol. 2004 Nov 15;173(10):6303-11.

  4. Effros RB, Dagarag M, Valenzuela HF. 
    In vitro senescence of immune cells.
    Exp Gerontol. 2003 Nov-Dec;38(11-12):1243-9. Review.

  5. Dagarag M, Ng H, Lubong R, Effros RB, Yang OO. 
    Differential impairment of lytic and cytokine functions in senescent human immunodeficiency virus type 1-specific cytotoxic T lymphocytes.
    J Virol. 2003 Mar;77(5):3077-83.

  6. Schmid I, Dagarag MD, Hausner MA, Matud JL, Just T, Effros RB, Jamieson BD. 
    Simultaneous flow cytometric analysis of two cell surface markers, telomere length, and DNA content.
    Cytometry. 2002 Nov 1;49(3):96-105.

HARNISHA DALWADI
Class of 1997
Laboratory of Dr. Jonathan Braun

  1. Dalwadi H, Bo W, Braun J. Related Articles, Links 
    Defining new pathogens and nonculturable infectious agents associated with   inflammatory bowel disease.
    Curr Opin Gastroenterol. 2000 Jan;16(1):56-59.

  2. Huang TT, Zong Y, Dalwadi H, Chung C, Miceli MC, Spicher K, Birnbaumer L, Braun J, Aranda R.
    TCR-mediated hyper-responsiveness of autoimmune Galphai2(-/-) mice is an intrinsic naive CD4(+) T cell disorder selective for the Galphai2 subunit.
    Int Immunol. 2003 Nov;15(11):1359-67.

  3. Dalwadi H, Wei B, Schrage M, Spicher K, Su TT, Birnbaumer L, Rawlings DJ, Braun J. 
    B cell developmental requirement for the G alpha i2 gene.
    J Immunol. 2003 Feb 15;170(4):1707-15. Erratum in: J Immunol. 2004 Jul 1;173(1):695.

  4. Wei B, Huang T, Dalwadi H, Sutton CL, Bruckner D, Braun J. 
    Pseudomonas fluorescens encodes the Crohn's disease-associated I2 sequence and T-cell superantigen.
    Infect Immun. 2002 Dec;70(12):6567-75.

  5. Sutton CL, Kim J, Yamane A, Dalwadi H, Wei B, Landers C, Targan SR, Braun J.
    Identification of a novel bacterial sequence associated with Crohn’s disease.
    2000. Gastroenterology 119:36-45.

  6. Wei B, Dalwadi H., Gordon LK, Landers C, Bruckner D, Targan SR, Braun J.
    Molecular cloning of a Bacteroides caccae TonB-linked outer membrane protein associated with inflammatory bowel disease.
    2001. Infect. Immun., 69:6044-6054.

  7. Dalwadi H, Wei B, Kronenberg M, Sutton CL, Braun, J.
    The Crohn’s disease-associated bacterial protein, I2, is a novel enteric T cell superantigen.
    2001. Immunity 15:149-158.

  8. Braun J, Sutton CL, Kim J, Yamane A, Dalwadi H, Wei B, Landers C, Targan SR.
    Optimal cases and sites to search for primacy microbial agents in Crohn's disease.
    2001. Gastroenterology 120, 1066-1067.

JOSHUA DEIGNAN - (Profile)
Class of 2002
Dr. Wayne Grody

  1. Deignan J.L., Livesay J.C., Yoo P.K., Goodman S.I., O'Brien W.E., Iyer R.K., Cederbaum S.D., Grody W.W. (2006)
    Ornithine Deficiency in the Arginase Double Knockout Mouse.
    Manuscript in press in Molecular Genetics and Metabolism, E.R.B. McCabe ed.

SVEN DEVOS
Class of 1998
Laboratory of Dr. Jonathan Said

  1. Tsukasaki K, Tanosaki S, DeVos S, Hofmann WK, Wachsman W, Gombart AF, Krebs J, Jauch A, Bartram CR, Nagai K, Tomonaga M, Said JW, Koeffler HP.
    Identifying progression-associated genes in adult T-cell leukemia/lymphoma by using oligonucleotide microarrays.
    Int J Cancer. 2004 May 10;109(6):875-81.

  2. de Vos S, Hofmann WK, Grogan TM, Krug U, Schrage M, Miller TP, Braun JG, Wachsman W, Koeffler HP, Said JW. Related Articles, Links
    Gene expression profile of serial samples of transformed B-cell lymphomas.
    Lab Invest. 2003 Feb;83(2):271-85.

CROMWELL ESPINEDA
Class of 1999
Laboratory of Dr. AK Rajasekaran

  1. Rajasekaran SA, Gopal J, Espineda C, Ryazantsev S, Schneeberger EE, Rajasekaran AK.
    HPAF-II, a cell culture model to study pancreatic epithelial cell structure and function.
    Pancreas. 2004 Oct;29(3):e77-83.
    PMID: 15367897 [PubMed - indexed for MEDLINE]

  2. Rajasekaran SA, Gopal J, Willis D, Espineda C, Twiss JL, Rajasekaran AK.
    Na,K-ATPase beta1-subunit increases the translation efficiency of the alpha1-subunit in MSV-MDCK cells.
    Mol Biol Cell. 2004 Jul;15(7):3224-32. Epub 2004 May 7.
    PMID: 15133131 [PubMed - indexed for MEDLINE]

  3. Espineda CE, Chang JH, Twiss J, Rajasekaran SA, Rajasekaran AK.
    Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma.
    Mol Biol Cell. 2004 Mar;15(3):1364-73. Epub 2003 Dec 29.
    PMID: 14699059 [PubMed - indexed for MEDLINE]

  4. Espineda C, Seligson DB, James Ball W Jr, Rao J, Palotie A, Horvath S, Huang Y, Shi T, Rajasekaran AK.
    Analysis of the Na,K-ATPase alpha- and beta-subunit expression profiles of bladder cancer using tissue microarrays.
    Cancer. 2003 Apr 15;97(8):1859-68.
    PMID: 12673711 [PubMed - indexed for MEDLINE]

Steven Fauce - (Profile)
Class of 2003
Laboratory of Dr. Rita Effros

  1. Fauce, S.R. and Effros, R.B.
    Telomerase dynamics in T cells: effect on immunity during aging and chronic infection.in Immunosenescence.
    (G. Pawelec, ed), Landes Bioscience, in press 2007.

  2. Steven R. Fauce, Otto O. Yang, & Rita B. Effros.
    Autologous CD4/CD8 co-culture assay: a physiologically-relevant composite measure of CD8+ T lymphocyte function in HIV-infected persons.
    Journal of Immunological Methods (in press).

JENNIFER FULCHER- (Profile)
Class of 2002
Laboratory of Dr. Benhur Lee

  1. Maldonado-Arocho FJ, Fulcher JA, Lee B, Bradley KA.
    Anthrax oedema toxin induces anthrax toxin receptor expression in monocyte-derived cells.
    Mol Microbiol. 2006 Jul;61(2):324-37.
    PMID: 16856939 [PubMed - indexed for MEDLINE]

  2. Fulcher JA, Hashimi ST, Levroney EL, Pang M, Gurney KB, Baum LG, Lee B.
    Galectin-1-matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix.
    J Immunol. 2006 Jul 1;177(1):216-26.
    PMID: 16785517 [PubMed - indexed for MEDLINE]

  3. Aguilar HC, Matreyek KA, Filone CM, Hashimi ST, Levroney EL, Negrete OA, Bertolotti-Ciarlet A, Choi DY, McHardy I, Fulcher JA, Su SV, Wolf MC, Kohatsu L, Baum LG, Lee B.
    N-glycans on Nipah virus fusion protein protect against neutralization but reduce membrane fusion and viral entry.
    J Virol. 2006 May;80(10):4878-89.
    PMID: 16641279 [PubMed - indexed for MEDLINE]

  4. Levroney EL, Aguilar HC, Fulcher JA, Kohatsu L, Pace KE, Pang M, Gurney KB, Baum LG, Lee B.
    Novel innate immune functions for galectin-1: galectin-1 inhibits cell fusion by Nipah virus envelope glycoproteins and augments dendritic cell secretion of proinflammatory cytokines.
    J Immunol. 2005 Jul 1;175(1):413-20.
    PMID: 15972675 [PubMed - indexed for MEDLINE]

NIMA GHARAVI
Class of 2001
Laboratory of Dr. Judith Berliner

  1. Gargalovic PS, Gharavi NM, Clark MJ, Pagnon J, Yang WP, He A, Truong A, Baruch-Oren T, Berliner JA, Kirchgessner TG, Lusis AJ. Related Articles, Links
    The Unfolded Protein Response Is an Important Regulator of Inflammatory Genes in Endothelial Cells.
    Arterioscler Thromb Vasc Biol. 2006 Aug 24; [Epub ahead of print]
    PMID: 16931790

  2. Gargalovic PS, Imura M, Zhang B, Gharavi NM, Clark MJ, Pagnon J, Yang WP, He A, Truong A, Patel S, Nelson SF, Horvath S, Berliner JA, Kirchgessner TG, Lusis AJ.
    Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids.
    Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12741-6. Epub 2006 Aug 15.
    PMID: 16912112

  3. Gharavi NM, Baker NA, Mouillesseaux KP, Yeung W, Honda HM, Hsieh X, Yeh M, Smart EJ, Berliner JA.
    Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids.
    Circ Res. 2006 Mar 31;98(6):768-76. Epub 2006 Feb 23.
    PMID: 16497987

  4. Yeh M, Gharavi NM, Choi J, Hsieh X, Reed E, Mouillesseaux KP, Cole AL, Reddy ST, Berliner JA. Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway.
    J Biol Chem. 2004 Jul 16;279(29):30175-81. Epub 2004 May 13.
    PMID: 15143062

JARED GOLDSTINE
Class of 2001
Laboratory of Dr. Harry Vinters

  1. Goldstine J, Seligson DB, Beizai P, Miyata H, Vinters HV.
    Tissue microarrays in the study of non-neoplastic disease of the nervous system.
    J Neuropathol Exp Neurol. 2002 Aug;61(8):653-62. Review.
    PMID: 12152780

Julia goodnough - (Profile)
Class of 2005
Laboratory of Dr. Tomas Ganz

  1. Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T.
    Iron-transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4
    Blood. 2007 May 31; [Epub ahead of print]

JOSEPH HERNANDEZ
Class of 2000
Laboratory of Dr. Linda Baum

  1. Hernandez JD, Nguyen JT, He J, Wang W, Ardman B, Green JM, Fukuda M, Baum LG.
    Galectin-1 Binds Different CD43 Glycoforms to Cluster CD43 and Regulate T Cell Death.
    J Immunol. 2006 Oct 15;177(8):5328-36.

  2. Hernandez JD, Baum LG.
    Ah, sweet mystery of death! Galectins and control of cell fate.
    Glycobiology. 2002 Oct;12(10):127R-36R. Review.
    PMID: 12244068 [PubMed - indexed for MEDLINE]

  3. Min Zhang, Miriana Moran, June Round, Teresa A. Low, Viresh P. Patel, Tamar Tomassian, Joseph D. Hernandez and M. Carrie Miceli,
     CD45 signals outside of lipid rafts to promote ERK activation, synaptic raft clustering, and IL-2 production.
    J Immunol. 2005 Feb 1;174(3):1479-90.

  4. Hahn HP, Pang M, He J, Hernandez JD, Yang RY, Li LY, Wang X, Liu FT, Baum LG.
    Galectin-1 induces nuclear translocation of endonuclease G in caspase- and cytochrome c-independent T cell death.
    Cell Death Differ. 2004 Dec;11(12):1277-86.

KURT HONG - (Profile)
Class of 2003
Laboratory of Dr. Jonathan Braun/D. Heber

  1. Belperio JA, Keane MP, Burdick MD, Gomperts BN, Xue YY, Hong K, Mestas J, Zisman D, Ardehali A, Saggar R, Lynch JP 3rd, Ross DJ, Strieter RM.
    CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury. J Immunol. 2005 Nov 15;175(10):6931-9.
    PMID: 16272353 [PubMed - indexed for MEDLINE]

  2. Hong KM, Burdick MD, Phillips RJ, Heber D, Strieter RM.
    Characterization of human fibrocytes as circulating adipocyte progenitors and the formation of human adipose tissue in SCID mice.
    FASEB J. 2005 Dec;19(14):2029-31. Epub 2005 Sep 27.
    PMID: 16188961 [PubMed - indexed for MEDLINE]

  3. Belperio JA, Keane MP, Burdick MD, Gomperts B, Xue YY, Hong K, Mestas J, Ardehali A, Mehrad B, Saggar R, Lynch JP, Ross DJ, Strieter RM.
    Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome.
    J Clin Invest. 2005 May;115(5):1150-62.
    PMID: 15864347

  4. Phillips RJ, Burdick MD, Hong K, Lutz MA, Murray LA, Xue YY, Belperio JA, Keane MP, Strieter RM.
    Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis.
    J Clin Invest. 2004 Aug;114(3):438-46.
    PMID: 15286810

KATRINA HOYER
Class of 1998
Laboratory of Dr. Mike Teitell

  1. Shen RR, Ferguson DO, Renard M, Hoyer KK, Kim U, Hao X, Alt FW, Roeder RG, Morse HC 3rd, Teitell MA.
    Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation.
    Blood. 2006 Sep 15;108(6):1991-8. Epub 2006 May 25.
    PMID: 16728701 [PubMed - in process]

  2. Hoyer KK, Herling M, Bagrintseva K, Dawson DW, French SW, Renard M, Weinger JG, Jones D, Teitell MA.
    T cell leukemia-1 modulates TCR signal strength and IFN-gamma levels through phosphatidylinositol 3-kinase and protein kinase C pathway activation.
    J Immunol. 2005 Jul 15;175(2):864-73.
    PMID: 16002684 [PubMed - indexed for MEDLINE]

  3. Hoyer KK, Pang M, Gui D, Shintaku IP, Kuwabara I, Liu FT, Said JW, Baum LG, Teitell MA.
    An anti-apoptotic role for galectin-3 in diffuse large B-cell lymphomas.
    Am J Pathol. 2004 Mar;164(3):893-902.
    PMID: 14982843 [PubMed - indexed for MEDLINE]

  4. Hoyer KK, French SW, Turner DE, Nguyen MT, Renard M, Malone CS, Knoetig S, Qi CF, Su TT, Cheroutre H, Wall R, Rawlings DJ, Morse HC 3rd, Teitell MA.
    Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma.
    Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14392-7. Epub 2002 Oct 14.
    PMID: 12381789 [PubMed - indexed for MEDLINE]

  5. French SW, Hoyer KK, Shen RR, Teitell MA.
    Transdifferentiation and nuclear reprogramming in hematopoietic development and neoplasia.
    Immunol Rev. 2002 Sep;187:22-39. Review.
    PMID: 12366680 [PubMed - indexed for MEDLINE]

LANDON INGE - (Profile)
Class of 2001
Laboratory of Dr. AK Rajasekaran

  1. Christiansen JJ, Rajasekaran SA, Inge L, Cheng L, Anilkumar G, Bander NH, Rajasekaran AK.
    N-glycosylation and microtubule integrity are involved in apical targeting of prostate-specific membrane antigen: implications for immunotherapy.
    Mol Cancer Ther. 2005 May;4(5):704-14.
    PMID: 15897234

  2. Choe G, Horvath S, Cloughesy TF, Crosby K, Seligson D, Palotie A, Inge L, Smith BL, Sawyers CL, Mischel PS.
    Related Articles, Links
    Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo.
    Cancer Res. 2003 Jun 1;63(11):2742-6.
    PMID: 12782577

PETER JINDRA - (Profile)
Class of 2002
Laboratory of Dr. Elaine Reed

  1. Jindra PT, Zhang X, Mulder A, Claas F, Veale J, Jin YP, Reed EF.
    Related Articles, Links
    Anti-HLA antibodies can induce endothelial cell survival or proliferation depending on their concentration.
    Transplantation. 2006 Jul 15;82(1 Suppl):S33-5.
    PMID: 16829793

  2. Jin YP, Jindra PT, Gong KW, Lepin EJ, Reed EF.
    Anti-HLA class I antibodies activate endothelial cells and promote chronic rejection.
    Transplantation. 2005 Feb 15;79(3 Suppl):S19-21. Review.
    PMID: 15699739 [PubMed - indexed for MEDLINE]

  3. Jin YP, Fishbein MC, Said JW, Jindra PT, Rajalingam R, Rozengurt E, Reed EF.
    Related Articles, Links
    Anti-HLA class I antibody-mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cells.
    Hum Immunol. 2004 Apr;65(4):291-302.
    PMID: 15120184 [PubMed - indexed for MEDLINE]

  4. Lepin EJ, Zhang Q, Zhang X, Jindra PT, Hong LS, Ayele P, Peralta MV, Gjertson DW, Kobashigawa JA, Wallace WD, Fishbein MC, Reed EF.
    Phosphorylated S6 ribosomal protein: a novel biomarker of antibody-mediated rejection in heart allografts.
    Am J Transplant.  2006 Jul;6(7):1560-71.
    PMID: 16827856 [PubMed - in process]

  5. .Jin YP, Korin Y, Zhang X, Jindra PT, Rozengurt E, Reed EF.
    RNA Interference Elucidates the Role of Focal Adhesion Kinase in HLA Class I-Mediated Focal Adhesion Complex Formation and Proliferation in Human Endothelial Cells.
    J Immunol. 2007 Jun 15;178(12):7911-22.

SEAN JOSEPH
Class of 1996
Laboratory of Dr. Peter Tontonoz

  1. Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L, Hogenesch J, O'connell RM, Cheng G, Saez E, Miller JF, Tontonoz P. 
    LXR-dependent gene expression is important for macrophage survival and the innate immune response.
    Cell. 2004 Oct 15;119(2):299-309.

  2. Walczak R, Joseph SB, Laffitte BA, Castrillo A, Pei L, Tontonoz P.  
    Transcription of the vascular endothelial growth factor gene in macrophages is regulated by liver X receptors.
    J Biol Chem. 2004 Mar 12;279(11):9905-11. Epub 2003 Dec 29.

  3. Xu J, Chang V, Joseph SB, Trujillo C, Bassilian S, Saad MF, Lee WN, Kurland IJ. 
    Peroxisomal proliferator-activated receptor alpha deficiency diminishes insulin-responsiveness of gluconeogenic/glycolytic/pentose gene expression and substrate cycle flux.
    Endocrinology. 2004 Mar;145(3):1087-95. Epub 2003 Dec 11.

  4. Castrillo A, Joseph SB, Vaidya SA, Haberland M, Fogelman AM, Cheng G, Tontonoz P. 
    Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism.
    Mol Cell. 2003 Oct;12(4):805-16.

  5. Laffitte BA, Chao LC, Li J, Walczak R, Hummasti S, Joseph SB, Castrillo A, Wilpitz DC, Mangelsdorf DJ, Collins JL, Saez E, Tontonoz P. 
    Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue.
    Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5419-24. Epub 2003 Apr 15.

  6. Joseph SB, Tontonoz P.
    LXRs: new therapeutic targets in atherosclerosis?
    Curr Opin Pharmacol. 2003 Apr;3(2):192-7. Review.

  7. Laffitte BA, Joseph SB, Chen M, Castrillo A, Repa J, Wilpitz D, Mangelsdorf D, Tontonoz P. 
    The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions.
    Mol Cell Biol. 2003 Mar;23(6):2182-91.

  8. Castrillo A, Joseph SB, Marathe C, Mangelsdorf DJ, Tontonoz P.
    Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages.
    J Biol Chem. 2003 Mar 21;278(12):10443-9. Epub 2003 Jan 16.

  9. Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P.
    Reciprocal regulation of inflammation and lipid metabolism by liver X receptors.
    Nat Med. 2003 Feb;9(2):213-9. Epub 2003 Jan 13.

  10. Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG.  
    Identification of macrophage liver X receptors as inhibitors of atherosclerosis.
    Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11896-901. Epub 2002 Aug 22.

  11. Xu J, Xiao G, Trujillo C, Chang V, Blanco L, Joseph SB, Bassilian S, Saad MF, Tontonoz P, Lee WN, Kurland IJ. 
    Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose production.
    J Biol Chem. 2002 Dec 27;277(52):50237-44. Epub 2002 Aug 9.

  12. Joseph SB, McKilligin E, Pei L, Watson MA, Collins AR, Laffitte BA, Chen M, Noh G, Goodman J, Hagger GN, Tran J, Tippin TK, Wang X, Lusis AJ, Hsueh WA, Law RE, Collins JL, Willson TM, Tontonoz P. 
    Synthetic LXR ligand inhibits the development of atherosclerosis in mice.
    Proc Natl Acad Sci U S A. 2002 May 28;99(11):7604-9.

  13. Mak PA, Laffitte BA, Desrumaux C, Joseph SB, Curtiss LK, Mangelsdorf DJ, Tontonoz P, Edwards PA. 
    Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta.
    J Biol Chem. 2002 Aug 30;277(35):31900-8. Epub 2002 May 24.

  14. Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, Collins JL, Osborne TF, Tontonoz P. Related Articles, Links  
    Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors.
    J Biol Chem. 2002 Mar 29;277(13):11019-25. Epub 2002 Jan 14.

CHRISTOPHER KERFOOT
Class of 1994
Laboratory of Dr. Harry Vinters

  1. Johnson MW, Kerfoot C, Bushnell T, Li M, Vinters HV.
    Hamartin and tuberin expression in human tissues.
    Mod Pathol. 2001 Mar;14(3):202-10.

  2. Kerfoot C, Vinters HV, Mathern GW. 
    Cerebral cortical dysplasia: giant neurons show potential for increased excitation and axonal plasticity.
    Dev Neurosci. 1999 Nov;21(3-5):260-70.

  3. Vinters HV, Park SH, Johnson MW, Mischel PS, Catania M, Kerfoot C. 
    Cortical dysplasia, genetic abnormalities and neurocutaneous syndromes.
    Dev Neurosci. 1999 Nov;21(3-5):248-59. Review.

  4. Vinters HV, Kerfoot C, Catania M, Emelin JK, Roper SN, DeClue JE. 
     Tuberous sclerosis-related gene expression in normal and dysplastic brain.
    Epilepsy Res. 1998 Sep;32(1-2):12-23. Review.

  5. Vinters HV, Kerfoot C, Emelin JK. 
     Tuberin loss from cerebral tissues.
    Ann Neurol. 1997 Aug;42(2):270-2. No abstract available.

  6. Park SH, Pepkowitz SH, Kerfoot C, De Rosa MJ, Poukens V, Wienecke R, DeClue JE, Vinters HV. 
     Tuberous sclerosis in a 20-week gestation fetus: immunohistochemical study.
    Acta Neuropathol (Berl). 1997 Aug;94(2):180-6.

  7. Kerfoot C, Wienecke R, Menchine M, Emelin J, Maize JC Jr, Welsh CT, Norman MG, DeClue JE, Vinters HV.
    Localization of tuberous sclerosis 2 mRNA and its protein product tuberin in normal human brain and in cerebral lesions of patients with tuberous sclerosis.
    Brain Pathol. 1996 Oct;6(4):367-75.

 

LUCIANA KOHATSU
Class of 2000
Laboratory of Dr. Linda Baum

  1. Kohatsu L, Hsu DK, Jegalian AG, Liu FT, Baum LG.
    Galectin-3 Induces Death of Candida Species Expressing Specific beta-1,2-Linked Mannans.
    J Immunol. 2006 Oct 1;177(7):4718-26.
    PMID: 16982911 [PubMed - in process]

  2. Aguilar HC, Matreyek KA, Filone CM, Hashimi ST, Levroney EL, Negrete OA, Bertolotti-Ciarlet A, Choi DY, McHardy I, Fulcher JA, Su SV, Wolf MC, Kohatsu L, Baum LG, Lee B.
    N-glycans on Nipah virus fusion protein protect against neutralization but reduce membrane fusion and viral entry.
    J Virol. 2006 May;80(10):4878-89.
    PMID: 16641279 [PubMed - indexed for MEDLINE]

  3. Levroney EL, Aguilar HC, Fulcher JA, Kohatsu L, Pace KE, Pang M, Gurney KB, Baum LG, Lee B. R
    Novel innate immune functions for galectin-1: galectin-1 inhibits cell fusion by Nipah virus envelope glycoproteins and augments dendritic cell secretion of proinflammatory cytokines.
    J Immunol. 2005 Jul 1;175(1):413-20.
    PMID: 15972675 [PubMed - indexed for MEDLINE]

CHIH-HUNG LAI
Class of 1998
Laboratory of Dr. Richard Gatti

  1. Nahas SA, Lai CH, Gatti RA. Related Articles, Links
    Post-irradiation phosphorylation of structural maintenance chromosome 1 (SMC1) is independent of the Fanconi protein pathway.
    Int J Radiat Oncol Biol Phys. 2005 Mar 15;61(4):1167-72.
    PMID: 15752898 [PubMed - indexed for MEDLINE]

  2. Lai CH, Chun HH, Nahas SA, Mitui M, Gamo KM, Du L, Gatti RA. Related Articles, Links
    Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons.
    Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15676-81. Epub 2004 Oct 21. Erratum in: Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16982.
    PMID: 15498871 [PubMed - indexed for MEDLINE]

  3. Coutinho G, Mitui M, Campbell C, Costa Carvalho BT, Nahas S, Sun X, Huo Y, Lai CH, Thorstenson Y, Tanouye R, Raskin S, Kim CA, Llerena J Jr, Gatti RA.
    Five haplotypes account for fifty-five percent of ATM mutations in Brazilian patients with ataxia telangiectasia: seven new mutations.
    Am J Med Genet A. 2004 Apr 1;126(1):33-40.
    PMID: 15039971 [PubMed - indexed for MEDLINE]

  4. Chun HH, Sun X, Nahas SA, Teraoka S, Lai CH, Concannon P, Gatti RA.
    Improved diagnostic testing for ataxia-telangiectasia by immunoblotting of nuclear lysates for ATM protein expression.
    Mol Genet Metab. 2003 Dec;80(4):437-43.
    PMID: 14654357 [PubMed - indexed for MEDLINE]

  5. Mitui M, Campbell C, Coutinho G, Sun X, Lai CH, Thorstenson Y, Castellvi-Bel S, Fernandez L, Monros E, Carvalho BT, Porras O, Fontan G, Gatti RA.
    Independent mutational events are rare in the ATM gene: haplotype prescreening enhances mutation detection rate.
    Hum Mutat. 2003 Jul;22(1):43-50.
    PMID: 12815592 [PubMed - indexed for MEDLINE]

MICHAEL LIN
Class of 1995
Laboratory of Dr. Kathleen Sakamoto

  1. Lin M, Chang JK, Shankar D, Sakamoto KM.
    The role of p55CDC in cell cycle control and mammalian cell proliferation, differentiation, and apoptosis.
    Exp Mol Pathol. 2003 Apr;74(2):123-8.

LAN LIN - (Profile)
Class of 2001
Laboratory of Dr. Tomas Ganz

  1. Lin L, Goldberg YP, Ganz T.
    Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin.
    Blood, 2005 Oct 15;106(8):2884-9

WEI LIU- (Profile)
Class of 2000
Laboratory of Dr. Kathleen Kelly

  1. Welter-Stahl L, Ojcius DM, Viala J, Girardin S, Liu W, Delarbre C, Philpott D, Kelly KA, Darville T.
    Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum.
    Cell Microbiol. 2006 Jun;8(6):1047-57.
    PMID: 16681844 [PubMed - indexed for MEDLINE]

  2. Liu W, Dubinett S, Patterson SL, Kelly KA. Related Articles, Links
    COX-2 inhibition affects growth rate of Chlamydia muridarum within epithelial cells.
    Microbes Infect. 2006 Feb;8(2):478-86. Epub 2005 Oct 5.
    PMID: 16297651 [PubMed - indexed for MEDLINE]

  3. Maxion HK, Liu W, Chang MH, Kelly KA.
    The infecting dose of Chlamydia muridarum modulates the innate immune response and ascending infection.
    Infect Immun. 2004 Nov;72(11):6330-40.
    PMID: 15501762 [PubMed - indexed for MEDLINE

KAN LU
Class of 1999
Laboratory of Dr. Paul Mischel

  1. Wang MY, Lu KV, Zhu S, Dia EQ, Vivanco I, Shackleford GM, Cavenee WK, Mellinghoff IK, Cloughesy TF, Sawyers CL, Mischel PS.
    Mammalian Target of Rapamycin Inhibition Promotes Response to Epidermal Growth Factor Receptor Kinase Inhibitors in PTEN-Deficient and PTEN-Intact Glioblastoma Cells.
    Cancer Res. 2006 Aug 15;66(16):7864-7869.
    PMID: 16912159 [PubMed - as supplied by publisher]

  2. Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R, Peck TC, Lee JC, Sellers WR, Stokoe D, Prados M, Cloughesy TF, Sawyers CL, Mischel PS.
    Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.
    N Engl J Med. 2005 Nov 10;353(19):2012-24. Erratum in: N Engl J Med. 2006 Feb 23;354(8):884.
    PMID: 16282176 [PubMed - indexed for MEDLINE]

  3. Lu KV, Jong KA, Kim GY, Singh J, Dia EQ, Yoshimoto K, Wang MY, Cloughesy TF, Nelson SF, Mischel PS.
    Differential induction of glioblastoma migration and growth by two forms of pleiotrophin.
    J Biol Chem. 2005 Jul 22;280(29):26953-64. Epub 2005 May 20.
    PMID: 15908427

  4. Lu KV, Jong KA, Rajasekaran AK, Cloughesy TF, Mischel PS.
    Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line.
    Lab Invest. 2004 Jan;84(1):8-20.
    PMID: 14631378

  5. Mischel PS, Shai R, Shi T, Horvath S, Lu KV, Choe G, Seligson D, Kremen TJ, Palotie A, Liau LM, Cloughesy TF, Nelson SF.
    Identification of molecular subtypes of glioblastoma by gene expression profiling.
    Oncogene. 2003 Apr 17;22(15):2361-73.
    PMID: 12700671

  6. Kim PS, Iyer RK, Lu KV, Yu H, Karimi A, Kern RM, Tai DK,
    Cederbaum SD, Grody WW.
    Expression of the liver form of arginase in erythrocytes.
    Mol Genet Metab. 2002 Jun;76(2):100-10.
    PMID: 12083807

  7. Horvath S, Zhang B, Carlson M, Lu KV, Zhu S, Felciano RM, Laurance MF, Zhao W, Qi S, Chen Z, Lee Y, Scheck AC, Liau LM, Wu H, Geschwind DH, Febbo PG, Kornblum HI, Cloughesy TF, Nelson SF, Mischel PS.
    Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target.
    Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17402-17407

HEATHER MAXION
Class of 1999
Laboratory of Dr. Kathleen Kelly

  1. Maxion HK, Liu W, Chang MH, Kelly KA.
    The infecting dose of Chlamydia muridarum modulates the innate immune response and ascending infection.
    Infect Immun. 2004 Nov;72(11):6330-40.
    PMID: 15501762 [PubMed - indexed for MEDLINE]

  2. Maxion HK, Kelly KA.
    Chemokine expression patterns differ within anatomically distinct regions of the genital tract during Chlamydia trachomatis infection.
    Infect Immun. 2002 Mar;70(3):1538-46.
    PMID: 11854242 [PubMed - indexed for MEDLINE]

HYEYOUNG MIN
Class of 1999
Laboratory of Dr. Kenneth Dorshkind

  1. Min H, Montecino-Rodriguez E, Dorshkind K.
    Effects of aging on the common lymphoid progenitor to pro-B cell transition.
    J Immunol. 2006 Jan 15;176(2):1007-12.
    PMID: 16393987 [PubMed - indexed for MEDLINE]

  2. Min H, Montecino-Rodriguez E, Dorshkind K.
    Reassessing the role of growth hormone and sex steroids in thymic involution.
    Clin Immunol. 2006 Jan;118(1):117-23. Epub 2005 Sep 26.
    PMID: 16188505 [PubMed - indexed for MEDLINE]

  3. Montecino-Rodriquez E, Min H, Dorshkind K.
    Reevaluating current models of thymic involution.

    Semin Immunol. 2005 Oct;17(5):356-61. Review.
    PMID: 15967677 [PubMed - indexed for MEDLINE]

  4. Min H, Montecino-Rodriguez E, Dorshkind K.
    Effects of aging on early B- and T-cell development.
    Immunol Rev. 2005 Jun;205:7-17. Review.
    PMID: 15882341 [PubMed - indexed for MEDLINE]

  5. Min H, Montecino-Rodriguez E, Dorshkind K.
    Reduction in the developmental potential of intrathymic T cell progenitors with age.
    J Immunol. 2004 Jul 1;173(1):245-50.
    PMID: 15210781 [PubMed - indexed for MEDLINE]

PATRICA MORA-GARCIA
Class of 1995
Laboratory of Kathleen Sakamoto

  1. Mora-Garcia P, Wei J, Sakamoto KM. 
    G-CSF induces stabilization of ETS protein Fli-1 during myeloid cell development.
    Pediatr Res. 2005 Jan;57(1):63-6. Epub 2004 Nov 19.

  2. Mora-Garcia P, Cheng J, Crans-Vargas HN, Countouriotis A, Shankar D, Sakamoto KM.
    Transcriptional regulators and myelopoiesis: the role of serum response factor and CREB as targets of cytokine signaling.
    Stem Cells. 2003;21(2):123-30. Review.

SHAWN MORALES
Laboratory of Dr. Jonathan Braun

  1. Ashley Forbes, Madhuri Wadehra, Sergei Mareninov, Shawn Morales, Kaori Shimazaki, Lynn K. Gordon, and Jonathan Braun. 
    The tetraspan protein EMP2 regulates expression of caveolin-1.
    J. Biol. Chem, 10.1074/jbc.M702117200.

JULIE NGUYEN
Class of 1994
Laboratory of Dr. Lind Baum

  1. Perillo NL, Uittenbogaart CH, Nguyen JT, Baum LG. 
    Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes.
    J Exp Med. 1997 May 19;185(10):1851-8.

  2. Vespa GN, Lewis LA, Kozak KR, Moran M, Nguyen JT, Baum LG, Miceli MC.
    Galectin-1 specifically modulates TCR signals to enhance TCR apoptosis but inhibit IL-2 production and proliferation.
    J Immunol. 1999 Jan 15;162(2):799-806.

  3. Hernandez JD, Nguyen JT, He J, Wang W, Ardman B, Green JM, Fukuda M, Baum LG. 
    Galectin-1 binds different CD43 glycoforms to cluster CD43 and regulate T cell death.
    J Immunol. 2006 Oct 15;177(8):5328-36.

  4. Nguyen JT, Evans DP, Galvan M, Pace KE, Leitenberg D, Bui TN, Baum LG.  
    CD45 modulates galectin-1-induced T cell death: regulation by expression of core 2 O-glycans.
    J Immunol. 2001 Nov 15;167(10):5697-707.

  5. Pace KE, Hahn HP, Pang M, Nguyen JT, Baum LG. Related Articles, Links 
    CD7 delivers a pro-apoptotic signal during galectin-1-induced T cell death.
    J Immunol. 2000 Sep 1;165(5):2331-4.

Dayo Oluwadara
Class of 2005
Laboratory of Dr. Paul Mischel

  1. Scupham AJ, Presley LL, Wei B, Bent E, Griffith N, McPherson M, Zhu F, Oluwadara O, Rao N, Braun J, Borneman J.
    Abundant and diverse fungal microbiota in the murine intestine.
    Appl Environ Microbiol. 2006 Jan;72(1):793-801.

LIMING PEI
Class of 2000
Laboratory of Dr. Peter Tontonoz

  1. Pei, L., Waki, H., Vaitheesvaran, B., Wilpitz, D.C., Kurland, I.J., and Tontonoz, P. (2006).
    NR4A orphan nuclear receptors are transcriptional regulators of helatic glucose metabolism.
    Nat. Med 12, 1048-1055.

  2. Baldan A, Pei L, Lee R, Tarr P, Tangirala RK, Weinstein MM, Frank J, Li AC, Tontonoz P, Edwards PA. (2006)
    Impaired development of atherosclerosis in hyperlipidemic Ldlr-/- and ApoE-/- mice transplanted with Abcg1-/- bone marrow.
    Arterioscler Thromb Vasc Biol. Oct;26(10):2301-7. Epub 2006 Aug 3.

  3. Chowq, E.k., Castrillo, A.., Shahangian, A., O’Connell, R.M., Pei, L., Modlin, R.L., Tontonoz, P., and Cheng, G.
    Critical role of IRF3-dependent RXR_repression in pathogen-associated metabolic diseases. (Manuscript under review in J Exp Med)

  4. Laffitte, B. A., Joseph, S. B., Walczak, R., Pei, L., Wilpitz, D. C., Collins, J. L., and Tontonoz, P. (2001).
    Autoregulation of the human liver X receptor alpha promoter.
    Mol Cell Biol 21, 7558-7568.

  5. Joseph, S. B., McKilligin, E., Pei, L., Watson, M. A., Collins, A. R., Laffitte, B. A., Chen, M., Noh, G., Goodman, J., Hagger, G. N., et al. (2002).
    Synthetic LXR ligand inhibits the development of atherosclerosis in mice.
    Proc Natl Acad Sci U S A 99, 7604-7609.

  6. Walczak, R., Joseph, S. B., Laffitte, B. A., Castrillo, A., Pei, L., and Tontonoz, P. (2004). Transcription of the vascular endothelial growth factor gene in macrophages is regulated by liver X receptors.
    J Biol Chem 279, 9905-9911.

  7. Joseph, S. B., Bradley, M. N., Castrillo, A., Bruhn, K. W., Mak, P. A., Pei, L., Hogenesch, J., O'Connell R, M., Cheng, G., Saez, E., et al. (2004).
    LXR-dependent gene expression is important for macrophage survival and the innate immune response.
    Cell 119, 299-309.

  8. Lin, J., Yang, R., Tarr, P. T., Wu, P. H., Handschin, C., Li, S., Yang, W., Pei, L., Uldry, M., Tontonoz, P., et al. (2005).
    Hyperlipidemic Effects of Dietary Saturated Fats Mediated through PGC-1beta Coactivation of SREBP.
    Cell 120, 261-273.

  9. Pei, L., Castrillo, A., Chen, M., Hoffmann, A., and Tontonoz, P. (2005).
    Induction of NR4A Orphan Nuclear Receptor Expression in Macrophages in Response to Inflammatory Stimuli.
    J Biol Chem 280, 29256-29262.

Gloria Preza
Class of 2005
Laboratory of Dr. Tomas Ganz

  1. Nemeth E, Preza GC, Jung CL, Kaplan J, Waring AJ, Ganz T.
    The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study.
    Blood. 2006 Jan 1;107(1):328-33. Epub 2005 Sep 1.
    PMID: 16141345

SETH RIVERA
Class of 2002
Laboratory of Dr. Tomas Ganz

  1. Pak M, Lopez MA, Gabayan V, Ganz T, Rivera S.
    Suppression of hepcidin during anemia requires erythropoietic activity.
    Blood. 2006 Aug 1; [Epub ahead of print]
    PMID: 16882706 [PubMed - as supplied by publisher]

  2. Rivera S, Nemeth E, Gabayan V, Lopez MA, Farshidi D, Ganz T.
    Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs.
    Blood. 2005 Sep 15;106(6):2196-9. Epub 2005 Jun 2.
    PMID: 15933050 [PubMed - indexed for MEDLINE]

  3. Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, Ganz T.
    Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia.
    Blood. 2005 Feb 15;105(4):1797-802. Epub 2004 Oct 12.
    PMID: 15479721 [PubMed - indexed for MEDLINE]

  4. Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T.
    IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin.
    J Clin Invest. 2004 May;113(9):1271-6.
    PMID: 15124018 [PubMed - indexed for MEDLINE]

STEVEN RIVERA
Class of 1995
Laboratory of Dr. Oliver Hankinson

  1. Saarikoski ST, Rivera SP, Hankinson O, Husgafvel-Pursiainen K.
    CYP2S1: A short review.
    Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):62-9.

  2.  Rivera SP, Choi HH, Chapman B, Whitekus MJ, Terao M, Garattini E, Hankinson O.
    Identification of aldehyde oxidase 1 and aldehyde oxidase homologue 1 as dioxin-inducible genes.
    Toxicology. 2005 Feb 28;207(3):401-9.

  3. Saarikoski ST, Rivera SP, Hankinson O.
    Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia.
    FEBS Lett. 2002 Oct 23;530(1-3):186-90.

  4. Rivera SP, Saarikoski ST, Hankinson O.  
    Identification of a novel dioxin-inducible cytochrome P450.
    Mol Pharmacol. 2002 Feb;61(2):255-9.

MATTHEW SCHRAGE - (Profile)
Class of 2001
Laboratory of Dr. Jonathan Said

  1. Ziring D, Wei B, Velazquez P, Schrage M, Buckley NE, Braun J.
    Related Articles, Links
    Formation of B and T cell subsets require the cannabinoid receptor CB2.
    Immunogenetics. 2006 Sep;58(9):714-25. Epub 2006 Aug 19.
    PMID: 16924491 [PubMed - in process]

  2. Thomas GV, Horvath S, Smith BL, Crosby K, Lebel LA, Schrage M, Said J, De Kernion J, Reiter RE, Sawyers CL.
    Antibody-based profiling of the phosphoinositide 3-kinase pathway in clinical prostate cancer.
    Clin Cancer Res. 2004 Dec 15;10(24):8351-6.
    PMID: 15623612 [PubMed - indexed for MEDLINE]

  3. Dalwadi H, Wei B, Schrage M, Spicher K, Su TT, Birnbaumer L, Rawlings DJ, Braun J.
    B cell developmental requirement for the G alpha i2 gene.
    J Immunol. 2003 Feb 15;170(4):1707-15. Erratum in: J Immunol. 2004 Jul 1;173(1):695.
    PMID: 12574334 [PubMed - indexed for MEDLINE]

  4. de Vos S, Hofmann WK, Grogan TM, Krug U, Schrage M, Miller TP, Braun JG, Wachsman W, Koeffler HP, Said JW. Related Articles, Links
    Gene expression profile of serial samples of transformed B-cell lymphomas.
    Lab Invest. 2003 Feb;83(2):271-85.

RHINE SHEN
Class of 2000
Laboratory of Dr. Mike Teitell

  1. Shen RR, Ferguson DO, Renard M, Hoyer KK, Kim U, Hao X, Alt FW, Roeder RG, Morse HC 3rd, Teitell MA.
    Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation. Blood, 15 September 2006, Vol. 108, No. 6, pp. 1991-1998.
    Prepublished online as a Blood First Edition Paper on May 25, 2006; DOI 10.1182/blood-2006-02-001354.

  2. Herling M, Teitell MA, Shen RR, Medeiros LJ, Jones D.
    TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin.
    Blood. 2003 Jun 15;101(12):5007-9. Epub 2003 Feb 6.
    PMID: 12576313 [PubMed - indexed for MEDLINE]

  3. French SW, Malone CS, Shen RR, Renard M, Henson SE, Miner MD, Wall R, Teitell MA.
    Sp1 transactivation of the TCL1 oncogene.
    J Biol Chem. 2003 Jan 10;278(2):948-55. Epub 2002 Nov 5.
    PMID: 12421830 [PubMed - indexed for MEDLINE]

  4. French SW, Hoyer KK, Shen RR, Teitell MA.
    Transdifferentiation and nuclear reprogramming in hematopoietic development and neoplasia.
    Immunol Rev. 2002 Sep;187:22-39. Review.
    PMID: 12366680 [PubMed - indexed for MEDLINE]

  5. French SW, Shen RR, Koh PJ, Malone CS, Mallick P, Teitell MA. Related Articles, Links
    A modeled hydrophobic domain on the TCL1 oncoprotein mediates association with AKT at the cytoplasmic membrane.
    Biochemistry. 2002 May 21;41(20):6376-82.
    PMID: 12009899 [PubMed - indexed for MEDLINE]

Robert Signer - (Profile)
Class of 2004
Laboratory of Dr. Ken Dorshkind

  1. Signer RA, Montecino-Rodriguez E, Witte ON, McLaughlin J, Dorshkind K.
    Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia.
    Blood. 2007 Jun 6; [Epub ahead of print]
    PMID: 17554060 [PubMed - as supplied by publisher]

  2. Signer RA, Montecino-Rodriguez E, Dorshkind K.
    Aging, B lymphopoiesis, and patterns of leukemogenesis.
    Exp Gerontol. 2007 May;42(5):391-5. Epub 2006 Dec 20.
    PMID: 17184948 [PubMed - in process]

SHANE G. SMITH
Class of 1998
Laboratory of Dr. Paul Mischel

  1. Mischel PS, Umbach JA, Eskandari S, Smith SG, Gundersen CB, Zampighi GA.
    Nerve growth factor signals via preexisting TrkA receptor oligomers.

    Biophys J. 2002 Aug;83(2):968-76.
    PMID: 12124278 [PubMed - indexed for MEDLINE]

BRIANNA STILLMAN
Class of 2001
Laboratory of Dr. Linda Baum

  1. Stillman BN, Hsu DK, Pang M, Brewer CF, Johnson P, Liu FT, Baum LG.
    Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death.
    J Immunol. 2006 Jan 15;176(2):778-89.
    PMID: 16393961 [PubMed - indexed for MEDLINE]

  2. Stillman BN, Mischel PS, Baum LG.
    New roles for galectins in brain tumors--from prognostic markers to therapeutic targets.
    Brain Pathol. 2005 Apr;15(2):124-32. Review.
    PMID: 15912884 [PubMed - indexed for MEDLINE]

HECTOR VALENZUELA
Class of 1994
Laboratory of Dr. Rita Effros

  1. Effros RB, Dagarag M, Valenzuela HF.
    In vitro senescence of immune cells.
    Exp Gerontol. 2003 Nov-Dec;38(11-12):1243-9. Review.

  2. Valenzuela HF, Effros RB.
    Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulus.
    Clin Immunol. 2002 Nov;105(2):117-25.

PETER VELAZQUEZ
Class of 2002
Laboratory of Dr. Jonathan Braun

  1. 1)  Ziring D, Wei B, Velazquez P, Schrage M, Buckley NE, Braun J. 
    Formation of B and T cell subsets require the cannabinoid receptor CB2.
    Immunogenetics.
    2006 Sep;58(9):714-25. Epub 2006 Aug 19.

  2. 2)  Huang T, Wei B, Velazquez P, Borneman J, Braun J. 
    Commensal microbiota alter the abundance and TCR responsiveness of splenic naive CD4+ T lymphocytes.
    Clin Immunol. 2005 Dec;117(3):221-30. Epub 2005 Nov 14.

  3. 3)  Wei B, Velazquez P, Turovskaya O, Spricher K, Aranda R, Kronenberg M, Birnbaumer L, Braun J. 
    Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets.
    Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2010-5. Epub 2005 Jan 31.

  4. 4)  Velazquez P, Wei B, Braun J.
    Surveillance B lymphocytes and mucosal immunoregulation.
    Springer Semin Immunopathol. 2005 Mar;26(4):453-62. Epub 2004 Dec 18. Review.

DEVENDRA VORA
Class of 1995
Laboratory of Dr. Judith Berliner

  1. Yeh M, Cole AL, Choi J, Liu Y, Tulchinsky D, Qiao JH, Fishbein MC, Dooley AN, Hovnanian T, Mouilleseaux K, Vora DK, Yang WP, Gargalovic P, Kirchgessner T, Shyy JY, Berliner JA.
    Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.
    Circ Res. 2004 Oct 15;95(8):780-8. Epub 2004 Sep 23.

  2. Cole AL, Subbanagounder G, Mukhopadhyay S, Berliner JA, Vora DK.
    Oxidized phospholipid-induced endothelial cell/monocyte interaction is mediated            by a cAMP-dependent R-Ras/PI3-kinase pathway.
    Arterioscler Thromb Vasc Biol. 2003 Aug 1;23(8):1384-90. Epub 2003 Jun 12.

KIMBERLY WALTON
Class of 1998
Laboratory of Dr. Judith Berliner

  1. Walton KA, Gugiu BG, Thomas M, Basseri RJ, Eliav DR, Salomon RG, Berliner JA.
    A role for neutral sphingomyelinase activation in the inhibition of LPS action by phospholipid oxidation products.
    J Lipid Res. 2006 Sep;47(9):1967-74. Epub 2006 Jun 14.
    PMID: 16775254 [PubMed - indexed for MEDLINE]

  2. Walton KA, Hsieh X, Gharavi N, Wang S, Wang G, Yeh M, Cole AL, Berliner JA.
    Receptors involved in the oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein.
    J Biol Chem. 2003 Aug 8;278(32):29661-6. Epub 2003 May 30.
    PMID: 12777373 [PubMed - indexed for MEDLINE]

  3. Walton KA, Cole AL, Yeh M, Subbanagounder G, Krutzik SR, Modlin RL, Lucas RM, Nakai J, Smart EJ, Vora DK, Berliner JA.
    Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2.
    Arterioscler Thromb Vasc Biol. 2003 Jul 1;23(7):1197-203. Epub 2003 May 29.
    PMID: 12775576 [PubMed - indexed for MEDLINE]

MICHAEL YEH
Class of 1999
Laboratory of Dr. Judith Berliner

  1. Gharavi NM, Baker NA, Mouillesseaux KP, Yeung W, Honda HM, Hsieh X, Yeh M, Smart EJ, Berliner JA.
    Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids.
    Circ Res. 2006 Mar 31;98(6):768-76. Epub 2006 Feb 23.
    PMID: 16497987 [PubMed - indexed for MEDLINE]

  2. Yeh M, Cole AL, Choi J, Liu Y, Tulchinsky D, Qiao JH, Fishbein MC, Dooley AN, Hovnanian T, Mouilleseaux K, Vora DK, Yang WP, Gargalovic P, Kirchgessner T, Shyy JY, Berliner JA.
    Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.
    Circ Res. 2004 Oct 15;95(8):780-8. Epub 2004 Sep 23.
    PMID: 15388640 [PubMed - indexed for MEDLINE

  3. Yeh M, Gharavi NM, Choi J, Hsieh X, Reed E, Mouillesseaux KP, Cole AL, Reddy ST, Berliner JA.
    Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway.
    J Biol Chem. 2004 Jul 16;279(29):30175-81. Epub 2004 May 13.
    PMID: 15143062 [PubMed - indexed for MEDLINE

  4. Walton KA, Hsieh X, Gharavi N, Wang S, Wang G, Yeh M, Cole AL, Berliner JA.
    Receptors involved in the oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein.
    J Biol Chem. 2003 Aug 8;278(32):29661-6. Epub 2003 May 30.
    PMID: 12777373 [PubMed - indexed for MEDLINE]

  5. Walton KA, Cole AL, Yeh M, Subbanagounder G, Krutzik SR, Modlin RL, Lucas RM, Nakai J, Smart EJ, Vora DK, Berliner JA.
    Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2.
    Arterioscler Thromb Vasc Biol. 2003 Jul 1;23(7):1197-203. Epub 2003 May 29.
    PMID: 12775576 [PubMed - indexed for MEDLINE]

  6. Srinivasan S, Yeh M, Danziger EC, Hatley ME, Riggan AE, Leitinger N, Berliner JA, Hedrick CC.
    Glucose regulates monocyte adhesion through endothelial production of interleukin-8.
    Circ Res. 2003 Mar 7;92(4):371-7. Epub 2003 Feb 13.
    PMID: 12600878 [PubMed - indexed for MEDLINE]

DIANA YOON
Class of 2000
Laboratory of Dr. Oliver Hankinson

  1. Beischlag TV, Taylor RT, Rose DW, Yoon D, Chen Y, Lee WH, Rosenfeld MG, Hankinson O.
    Recruitment of thyroid hormone receptor/retinoblastoma-interacting protein 230 by the aryl hydrocarbon receptor nuclear translocator is required for the transcriptional response to both dioxin and hypoxia.
    J Biol Chem. 2004 Dec 24;279(52):54620-8. Epub 2004 Oct 13.
    PMID: 15485806 [PubMed - indexed for MEDLINE]

  2. Yoon DY, Buchler P, Saarikoski ST, Hines OJ, Reber HA, Hankinson O.
    Identification of genes differentially induced by hypoxia in pancreatic cancer cells.
    Biochem Biophys Res Commun. 2001 Nov 9;288(4):882-6.

JAMES J. YUN
Class of 1999
Laboratory of Dr. Judith Berliner

  1. Yun JJ, Whiting D, Fischbein MP, Banerji A, Irie Y, Stein D, Fishbein MC, Proudfoot AE, Laks H, Berliner JA, Ardehali A.
    Combined blockade of the chemokine receptors CCR1 and CCR5 attenuates   chronic rejection.
    Circulation. 2004 Feb 24;109(7):932-7. Epub 2004 Feb 2.
    PMID: 14757698 [PubMed - indexed for MEDLINE]

  2. Yun JJ, Fischbein MP, Whiting D, Irie Y, Fishbein MC, Burdick MD,          Belperio J, Strieter RM, Laks H, Berliner JA, Ardehali A.
    The role of MIG/CXCL9 in cardiac allograft vasculopathy.
    Am J Pathol. 2002 Oct;161(4):1307-13.
    PMID: 12368204 [PubMed - indexed for MEDLINE]